Phorbol myristoyl acetate

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August undefined, 2024

WebMW 616.83, Purity > 99%. Potent nanomolar activator of protein kinase C in vivo and in vitro. Binds to C1 domain of protein kinase C, induces membrane translocation and enzyme…. …

Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - EMD Millipore

WebJun 30, 1988 · It is concluded that phorbol esters stereospecifically enhance the Ca 2+ -sensitivity of glutamate release, but that higher concentrations may be required than for protein kinase C translocation in the same preparation. Instead the enhancement may be related to the rapid inactivation of protein kinase C which occurs with phorbol esters. … WebA phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA. Entry Term (s) 12-Myristoyl-13-acetylphorbol 12-O-Tetradecanoyl Phorbol 13-Acetate Phorbol Myristate Acetate Tetradecanoylphorbol Acetate, 4a alpha-Isomer Pharm Action Carcinogens Registry Number NI40JAQ945 cyracom language list

Phorbol myristate acetate (PMA) - InvivoGen

WebJun 3, 2024 · I want to use the PMA solution to stimulate THP-1 (1x106 cells/ml), so I will choose one tube of PMA and dilute it by adding 990uL PBS so that the concentration of PMA reach to 10ug/ml. 25uL PMA ... WebZoom. Phorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS. WebMay 1, 2024 · Abstract Introduction: THP-1 cells, a human leukemia monocytic cell line, differentiated by phorbol myristate acetate (PMA) are widely used as surrogate of human … cy rabbit\u0027s-foot

4-1BB agonism: adding the accelerator to cancer …

Phorbol 12-myristate 13-acetate (PMA), PKC activator …

WebCD3, CD28, phorbol myristoyl acetate (PMA), ionomycin, phytohemagglutinin, interleukin (IL)-2, or IL-4 [4]. On 3, NK cells, 4-1BB is upregulated following ligation of the FcRγIII Fc receptor (CD16) by the Fc portion of mAb. In addition to activated immune effectors, 4-1BB is also expressed on innate immune cell populations, including WebPhorbol 12-myristate 13-acetate, 97%, Thermo Scientific Chemicals Catalog number: 356150050 Each Add to cart Ionomycin, 96% Catalog number: J62448.MCR 87.80 Each … binary tree left and rightWebPhorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a phorbol ester and PKC activator. 1, 2, 3, 4, 5 It activates the PKC isoforms PKCα, -β, -γ, -δ, -ε, -η, and -θ but not PKCζ or -ι/λ. 2 PMA (1-10 ng/ml) induces NF-κB-dependent gene expression in a reporter assay. 3 It promotes the differentiation … cyra 40 tablet

"Web3株钩体均在EMJH培养基中置28 ℃需氧培养至对数期备用。佛波酯(phorbol myristoyl acetate, PMA)购自Sigma公司，SYBR®PrimeScriptTMRT-PCR Kit购自大连TaKaRa公司，人细胞因子ELISA试剂盒购自R&D公司，ABI 7500 Fast为美国应用生物系统公司产品。 ... " - Phorbol myristoyl acetate

Phorbol myristoyl acetate

Low‐dose diet supplement of a natural flavonoid, luteolin, ameliorates …

WebPhorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. Cell Signal. 17(3):299-310. 3. Fürstenberger G. et al., 1981. Skin tumor promotion by phorbol esters is a two-stage process. PNAS. 78(12):7722-6. TECHNICAL SUPPORT WebMar 13, 2007 · Fig. 1 C and D also shows that emptying intracellular calcium stores in zero external calcium with either vasopressin, acting through a Gq-coupled hormone receptor, or the SERCA pump inhibitor, Tg, produces robust calcium entry when extracellular calcium is …

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WebSAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 24-Dec-2024 Revision Number 4 1. Identification Product Name Phorbol 12-myristate 13-acetate Cat No. : BP685, BP685-1, BP685-10, BP685-5 CAS No 16561-29-8 Synonyms PMA Recommended Use Laboratory chemicals. Uses advised against Food, drug, pesticide or biocidal product use. … WebIn order to test the biological relevance and potential interaction of MLK 3 with protein kinase C-mediated signaling pathways, human MLK 3 was stably expressed in rat glomerular mesangial cells using a retroviral vector (LXSN) and the effects of phorbol myristoyl acetate (PMA) on DNA synthesis and osteopontin mRNA expression were examined.

WebMixed lineage kinase 3 inhibits phorbol myristoyl acetate-induced DNA synthesis but not osteopontin expression in rat mesangial cells Authors Narayanan Parameswaran 1 , … WebMar 31, 2016 · Some of the canonic immunostimulatory agents known to induce 4-1BB upregulation on T cells include: Con A, plate-bound anti-CD3, CD28, phorbol myristoyl acetate (PMA), ionomycin, phytohemagglutinin, interleukin (IL)-2, or IL-4 [3, 4]. On NK cells, 4-1BB is upregulated following ligation of the FcRγIII Fc receptor (CD16) by the Fc portion of …

WebPhorbol 12-Myristate 13-Acetate (Clear or Whitish Film) PMA is an activator of Protein Kinase C; it is a skin irritant and mouse skin tumor promoter. Specifications WebPhorbol 12-myristate 13-acetate is a tumor promoter. Phorbol 12-myristate 13-acetate can also induce differentiation of THP-1 monocytes to a …

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WebProduct Name Phorbol 12-myristate 13-acetate Cat No. : BP685, BP685-1, BP685-10, BP685-5 CAS No 16561-29-8 Synonyms PMA Recommended Use Laboratory chemicals. Uses … binary tree listWebPhorbol 12-myristate 13-acetate Synonym (s): Phorbol-12-myristate-13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, PMA, TPA Empirical Formula (Hill Notation): C36H56O8 CAS No.: 16561-29-8 Molecular Weight: 616.83 Beilstein No.: 2407201 cyracom in phoenixWebMar 31, 2024 · Definition. A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA. Structure. Top Interacting. Genes. 0 50 100 150 200 250 MMP9 PTGS2 IL2 MAPK3 MAPK1 TNF IL6 JUN RELA CXCL8 Interactions. Actor name. Interactions with Tetradecanoylphorbol Acetate. binary tree machine learningWebPhorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a reversible, highly potent activator of protein kinase C (PKC), including Group A and Group B isoforms (Blumberg). PMA activates PKC isoforms through the binding of the C1 domain (Hurley et al.). PMA … binary tree list representationWebA phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA. Entry Term(s) 12-Myristoyl-13 … cyracom interpreter hotlineWebPhorbol 12-myristate 13-acetate Synonym (s): Phorbol-12-myristate-13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12 … cyracom international medinaWebFeb 24, 2014 · Luteolin (LU) is a potent natural mast cell stabilizer. However, a direct correlation between LU and these common metabolic diseases is not established. Methods and results Male C57BL/6 mice were fed low-fat diet, high-fat diet (HFD), HFD with 0.002 and 0.01% LU for 12 wk, respectively. binary tree maker