Cisplatin and hypokalemia
http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf Webactivity of cisplatin [see Clinical Pharmacology (12.1), Clinical Studies (14)]. • Administer PEDMARK 6 hours after completion of a cisplatin infusion. • For multiday cisplatin regimens, administer PEDMARK 6 hours after completion of each cisplatin infusion and at least 10 hours before the next cisplatin infusion. Do not
Cisplatin and hypokalemia
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WebApr 15, 2024 · Eventually, nephrotoxicity complicated by hypomagnesaemia was confirmed, and cisplatin-induced nephrotoxicity led to the final diagnosis of a familial form of …
WebNov 24, 2024 · fast, slow, or irregular heartbeat. headache (sudden and severe) hives, itching, skin rash. inability to speak. nervousness. noisy breathing. pain or discomfort in the arms, jaw, back, or neck. pounding in the ears. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. WebSep 1, 2024 · Cisplatin for injection can cause severe hypersensitivity reactions, including anaphylaxis and death. Manifestations have included facial edema, wheezing, tachycardia, and hypotension. Hypersensitivity reactions have occurred within minutes of administration to patients with prior exposure toCisplatin for injection.
WebDec 17, 2024 · Hypokalemia is defined as a serum or plasma potassium that is less than the normal value. Most reference laboratories establish the lower pediatric limit of normal serum potassium between 3 and 3.5 mEq/L. However, symptoms are unlikely to occur in most healthy children until serum potassium is below 3 mEq/L. WebJun 2, 2024 · Background: Cisplatin-associated acute kidney injury (C-AKI) is common. Predictive factors of C-AKI include age > 60 years, hypertension, cisplatin dose, diabetes, and serum albumin < 3.5g/L. The association between C-AKI and hypokalemia, hypomagnesemia or hyponatremia has not been well characterized to date.
WebDec 17, 2024 · Hypokalemia is defined as a serum or plasma potassium that is less than the normal value. Most reference laboratories establish the lower pediatric limit of normal …
WebFirst-line multiagent chemotherapy comprises doxorubicin, cisplatin, and high-dose methotrexate (MAP regimen) . ... Regarding toxicity, rash and hypokalemia was the most common grade 3 adverse event, and one death from end organ failure was reported that was possibly related to the drug. on splWebHypokalemia may develop with furosemide, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids, ACTH, licorice in large amounts, or prolonged use of laxatives. ... There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In ... ons planWebMar 5, 2014 · Cisplatin is a coordinate metal complex with significant antineoplastic activity, and its side effects include acute and chronic renal insufficiency, renal magnesium … onsplayer macWebThe Radiation Therapy Oncology Group launched a phase III trial to test the hypothesis that adding cetuximab to the radiation-cisplatin platform improves progression-free survival (PFS).Patients and methodsEligible patients with stage III or IV HNC were randomly assigned to receive radiation and cisplatin without (arm A) or with (arm B) cetuximab. ons planning permissionsWebNational Center for Biotechnology Information onsplayersWebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative … iogear downloadWebOther (less than 2%): Anaphylaxis, bronchospasm, tachycardia, angina, hypokalemia, electrocardiographic alterations, vascular occlusive events, and grand mal seizures. Except for bronchospasm and anaphylaxis, the relationship to ondansetron is unclear. ... More than 90% of patients receiving a cisplatin dose greater than or equal to 50 mg/m 2 ... onsplayer pc